CORE PLATFORM
The point-of-care platform
OVERVIEW
Achira’s platform enables a microfluidics-based point-of-care (POC) platform, featuring a fluorescence-based reader (with a touch screen interface and display), integrated microfluidic cartridges equipped with our patented hydrogel technology and a sophisticated optics module that utilises optimized machine learning algorithms to produce highly accurate results . This microfluidics approach offers numerous advantages for medical test performance at the point-of-care. Through platform miniaturization, our hydrogel sensors utilize minimal reagent volumes, ensuring economies of scale and affordable testing. The sophisticated fluidics enable precisely controlled, rapid, and multiplexed immunoassays with only a small volume of blood or serum, thus elevating the performance and reliability of POC tests. Leveraging these diverse aspects of the platform, our technology produces products that deliver lab-quality results for doctors’ offices, laboratories, and field testing.
The fundamental test principle involves embedding reagent-bound hydrogel sensors within a microfluidic cartridge. These sensors interact with analytes from samples and fluorescently labeled secondary reagents. Assays are performed in an integrated format by loading the sample, hydrogel sensor and reagents into an integrated cartridge that is loaded into a reader that automates flow and incubation steps before sensitive fluorescence detection takes place during readout.